Epidemiological Survey of Asymptomatic Bacteriuria in Diabetes Mellitus Patients in Patna, India

To determine the prevalence and etiology of Asymptomatic bacteriuria (ASB) and antimicrobial resistance of urinary isolates among diabetics mellitus and non-diabetics, a total of 200 patients comprising of 120 diabetes mellitus (DM) and 80 nondiabetes were studied. ASB was detected in 36% patients of which 40% are diabetic and 30% are non-diabetic. Coagulase Negative Staphylococcus (CoNS) were the predominant organism (36.36%) isolated from the urine of both diabetic and non-diabetic. We observed occurrence of ASB significantly increases with age in DM patients and is more prevalent in DM females compared to non-DM females. Whereas Klebsiella sp., Candida sp., and E. coli were also significantly more prominent in DM patients. Most isolates of Klebsiella sp. and E. coli showed resistances to multiple antibiotics tested. For the uropathogens found in the samples tested Levofloxacin proved to be the most sensitive antibiotic. The study revealed a high prevalence of ASB among DM than non-DM subjects. This study also demonstrates multiple drug resistance observed in both DM and non-DM subjects, therefore irrational and indiscriminate use of antibiotic should be avoided.